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CodingMotif: exact determination of overrepresented nucleotide motifs in coding sequences
2012
BMC Bioinformatics
It has been increasingly appreciated that coding sequences harbor regulatory sequence motifs in addition to encoding for protein. These sequence motifs are expected to be overrepresented in nucleotide sequences bound by a common protein or small RNA. However, detecting overrepresented motifs has been difficult because of interference by constraints at the protein level. Sampling-based approaches to solve this problem based on codon-shuffling have been limited to exploring only an infinitesimal
doi:10.1186/1471-2105-13-32
pmid:22333114
pmcid:PMC3298695
fatcat:ek7aej3b3remvgj3l6ket62fsm