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A simple method for statistical analysis of intensity differences in microarray-derived gene expression data
2001
BMC Biotechnology
Microarray experiments offer a potent solution to the problem of making and comparing large numbers of gene expression measurements either in different cell types or in the same cell type under different conditions. Inferences about the biological relevance of observed changes in expression depend on the statistical significance of the changes. In lieu of many replicates with which to determine accurate intensity means and variances, reliable estimates of statistical significance remain
pmid:11690545
pmcid:PMC59472
fatcat:dhphve7oqra4pmg56kr7uq6oti