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MSOAR: A High-Throughput Ortholog Assignment System Based on Genome Rearrangement
2007
Journal of Computational Biology
The assignment of orthologous genes between a pair of genomes is a fundamental and challenging problem in comparative genomics, since many computational methods for solving various biological problems critically rely on bona fide orthologs as input. While it is usually done using sequence similarity search, we recently proposed a new combinatorial approach that combines sequence similarity and genome rearrangement. This paper continues the development of the approach and unites genome
doi:10.1089/cmb.2007.0048
pmid:17990975
fatcat:q6pso2acsvfdxbjh2ymoodrg3i