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The field of systems biology has attracted the attention of biologists, engineers, mathematicians, physicists, chemists and others in an endeavour to create systems-level understanding of complex biological networks. In particular, systems engineering methods are finding unique opportunities in characterizing the rich behaviour exhibited by biological systems. In the same manner, these new classes of biological problems are motivating novel developments in theoretical systems approaches. Hence,doi:10.1098/rsif.2006.0143 pmid:16971329 pmcid:PMC1664650 fatcat:rqtnqq6ulvc5ldya75qha7di5u