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In this paper, we propose a calculation model for a crossflow filtration process that is applicable to polydispersed slurry microfiltration. The deposition velocity of particles in slurry, particle distribution, and resistance of the filter cake on the surface of the filtration media can be predicted by this model, and can be used to predict the variations of filtration velocity. The theoretical prediction matched well with the experimental data, having a difference within 20%, except for thedoi:10.3390/w12020489 fatcat:qrrevjnmqrf5xcowf23zqzm7p4