The pulp cavity is the most complex structure in nature. Mandibular molar demonstrates considerable variations with respect to additional canals or roots. Aim: The main aim of this radiographic study is to detect the presence of Middle Mesial [MM] canal in mandibular first and second molars. In this study the primary outcome was to check the prevalence in mandibular first and second molars and the secondary outcome is to analyse the configuration/types of middle mesial canal. Materials and

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... ds: A 50 CBCT were collected, 100 mandibular first molar and 100 mandibular second molars were analysed in all the three spatial planes. The inclusion criteria as follows: presence of bilateral mandibular molars with no resorption or any cracks or lesion. Results: 89 teeth had MM canal out of 200 teeth observed. In mandibular first molar 59 teeth were present, in mandibular molar 30 teeth present with MM canal. Bilateral predilections were found to be 66 teeth. The Significance difference was observed stating the first molar had more occurrence than the second molar. Conclusion: The clinician should have adequate knowledge to identify the presence of additional orifice present between Mesio-Bucaal [MB] and Mesio-lingual [ML] canal orifices. Clinical Significance: The understanding of the complex anatomy of the tooth is the key to the success of endodontic treatment. The careful interpretation of the radiograph, use of magnification, latest instruments, proper irrigation protocol and sealing of all portals of exit leads to the successful treatment.