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HPV induced tongue cancer in pregnancy: Diagnosis and the role of vaccination in management

Panagiotis Tsikouras, Anastasia Bothou, Konstantinos Paraskevopoulos, Xanthoula Anthoulaki, Anna Chalkidou, Ioannis Tsirkas, Fotini Gaitatzi, Michael Koutsogiannis, Stavroglou Athanasia, Apostolos Lazarou, George Dragoutsos, Konstantinos Nikolettos (+7 others)
2020 Clinical Obstetrics Gynecology and Reproductive Medicine  

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Oral cancer is frequently a squamous cell carcinoma. In Western countries it is more commonly found on the tongue and consists one of the most common malignancies in the oral mucosa. The exact causes of squamous cell carcinoma are not known. There are many risk factors such as chemical, biological, natural and other related to culture, habits, customs and traditions, religion and environmental influences at the national level and differ in different nations. Biological agents are viruses (such
more » ... s the herpes simplex virus, HPV, HIV) and mycoses. Human papillomavirus (HPV), especially HPV subtype 16, is on the rise in young people with oral cancer who are not smokers. Epidemiological studies throughout world with the help of molecular techniques undoubtedly show the crucial importance of human papillomavirus (HPV) in growth squamous cell carcinoma. The sensitive anatomical unit of the tongue in cases of malignancy in pregnant women creates significant bioethical concerns that must be addressed with delicacy, discernment and responsibility by the oncology medical team. The contribution of the 9 valent vaccination, which provides protection against this oncogenic subtype of HPV 16 associated with squamous cell carcinoma, is likely to be valuable to young women and men, and may be recommended after future studies during pregnancy. Tsikouras P (2020) HPV induced tongue cancer in pregnancy: Diagnosis and the role of vaccination in management Conclusion HPV infection usually does not pose a major medical risk, but often social outbreaks should not cause panic, but frequent clinical screening should be considered, if necessary, and early treatment of suspected lesions, if found in the oral cavity. Moreover, HPV vaccine should be encouraged to both sexes in order to protect them not only from cancer of genital organs, but also from tongue cancer.
doi:10.15761/cogrm.1000310 fatcat:fytop5zxovbwdl5a2uzzee3tby
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Panagiotis Tsikouras, Anastasia Bothou, Konstantinos Paraskevopoulos, Xanthoula Anthoulaki, Anna Chalkidou, Ioannis Tsirkas, Fotini Gaitatzi, Michael Koutsogiannis, Stavroglou Athanasia, Apostolos Lazarou, George Dragoutsos, Konstantinos Nikolettos, Panagiotis Petsidis, Stefanos Zervoudis, George Iatrakis, George Galazios, Ioannis Astridis, Nikolaos Nikolettos, Konstantinos Vahtsevanos. "HPV induced tongue cancer in pregnancy: Diagnosis and the role of vaccination in management." Clinical Obstetrics Gynecology and Reproductive Medicine (2020)