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Vascular lesions produced by renal cortical extracts of spontaneously hypertensive rats (SHR)
Japanese Heart Journal
From the renal cortical extracts of spontaneously hypertensive rats (SHR) and normal rats, the fraction without pressor effect but with vascular necrotizing effect (F3) and the fraction with pressor effect (F4) were isolated and compared. The pressor effect of F4 showed no difference between SHR and normal rats. Vascular lesions of the mesentery and pancreas produced by renal extracts were examined light microscopically and electron microscopically to compare the vascular necrotizing effects ofpmid:731923 fatcat:pukhpfuinvfbpoxmnguksyodzi