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Activation of glycogen synthase in myocardium induced by intermittent hypoxia is much lower in fasted than in fed rats
American Journal of Physiology. Endocrinology and Metabolism
Activation of glycogen synthase in myocardium induced by intermittent hypoxia is much lower in fasted than in fed rats. Obstructive sleep apnea is characterized by intermittent obstruction of the upper airway, which leads to intermittent hypoxia. Myocardial glycogen is a major energy resource for heart during hypoxia. Previous studies have demonstrated that intermittent hypoxia rapidly degrades myocardial glycogen and activates glycogen synthase (GS). However, the underlying mechanisms remaindoi:10.1152/ajpendo.00486.2006 pmid:17003235 fatcat:lhqlk4wtwzatnktgsxekgawy54