Three component reaction of indane-1,2,3-trione, tosylmethyl isocyanide and benzoic acid derivatives

2008 ARKIVOC  
The Passerini reactions of indane-1,2,3-trione, tosylmethyl isocyanide, and benzoic acid derivatives proceed at room temperature giving sterically congested 2,2-disubstituted indane-1,3dione derivatives in quantitative yield. The reactions are one-pot, and the products obtained did not require any purification.
doi:10.3998/ark.5550190.0009.f15 fatcat:sui7wtargjdprpiluiy2jjgiti