A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is
Recently, a metabolic shift between the increased cytoplasmic glycolysis and decreased mitochondrial respiration in cellular energy production has been regarded as a biological hallmark for human cancers. As speculated by Warburg in the 1950s, respiratory complexes (i.e., mitochondria in modern terminology) were impaired or suppressed in human cancers, and such a defect may play an important role in the carcinogenesis and progression of human cancer. To appraise the mitochondrial defect,doi:10.1016/j.fjs.2013.04.002 fatcat:zmr47dn42rfnxc42towghi3fve