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Signet ring cell carcinoma is a subtype of adenocarcinoma and mainly originated from stomach. Terminal ileum involvement is uncommon and only 2 cases have been reported in the literature. We represent a case of signet ring cell carcinoma of the terminal ileum showing gross features mimicking Crohn's disease in a patient with ankylosing spondylitis.doi:10.4081/gi.2013.e2 fatcat:dgx635b6bvesvi43b3jttunotq