Perindopril-associated pneumonitis

A. Benard, B. Melloni, B. Gosselin, F. Bonnaud, B. Wallaert
1996 European Respiratory Journal  
We report two cases of perindopril-associated pneumonitis with typical drug-induced clinical features. In the first case, biopsies showed granulomatous sarcoid-like lesions; in the second, bronchial wall eosinophil infiltration was reported with increased blood eosinophil count. In these two cases, improvement was obtained by withdrawal of the drug and was completed with steroids. All other causes were ruled out. Angiotensin-converting enzyme inhibitor (ACEI)-induced pneumonitis is still rare but has to be recognized as a real side-effect.
doi:10.1183/09031936.96.09061314 pmid:8804953 fatcat:ifwj6iw62zcrrewiy7l47p7t4q