Fosfomycin Dosing Regimens based on Monte Carlo Simulation for Treated Carbapenem-Resistant Enterobacteriaceae Infection

Sukrit Kanchanasurakit, Wichai Santimaleeworagun, Charles E. McPherson, Napacha Piriyachananusorn, Benjawan Boonsong, Papanin Katwilat, Surasak Saokaew
2020 Infection & Chemotherapy  
Infections by Carbapenem-Resistant Enterobacteriaceae (CRE) remain a leading cause of death in critically ill patients. Fosfomycin has been regarded as an alternative therapy for treatment of infections caused by CRE organisms. The purpose of this study is to evaluate clinical outcomes amongst patients with CRE infection who are receiving a fosfomycin dosing regimen using a Monte Carlo simulation and fosfomycin minimum inhibitory concentration (MIC).
doi:10.3947/ic.2020.52.4.516 fatcat:wveoooumqfhp3an4xjni62vrl4