Abstract. Chronic rheumatic heart disease (СRHD) continues to hold a leading position among the most urgent problems of clinical medicine. In recent years, in the literature there are many publications dealing with problems of atherothrombosis in rheumatic diseases, however, they relate mainly to diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA), and in which no data on the relationship of rheumatism and arteriosclerosis.