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Quantification of fast molecular adhesion by fluorescence footprinting
Rolling adhesion is a unique process in which the adhesion events are short-lived and operate under highly nonequilibrium conditions. These characteristics pose a challenge in molecular force quantification, where in situ measurement of these forces cannot be achieved with molecular force sensors that probe near equilibrium. Here, we demonstrated a quantitative adhesion footprint assay combining DNA-based nonequilibrium force probes and modeling to measure the molecular force involved in fastdoi:10.1126/sciadv.abe6984 fatcat:ij7d2n66jzdjzgbgrgwpvcu37q