BIOEQUIVALENCE STUDIES

Mihajlo B Jakovljević, Slobodan M Janković
2006 Acta Medica Medianae  
Development of pharmaceutical technology and occurence of different dosage forms and routes of administration of the same, well-known drugs leaded to greater role of bioequivalence testing. In this review, we would like to emphasize some aspects of bioequivalence testing between brand name and generic drug forms in both in vitro and in vivo conditions. We also consider important to present some examples of negative bioequivalence from marketed products in the past, together with the serious
more » ... ith the serious cosequences of their use.
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