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F1000 - Post-publication peer review of the biomedical literature
Eukaryotic Ca 2+ regulation involves sequestration into intracellular organelles, and expeditious Ca 2+ release into the cytosol is a hallmark of key signaling transduction pathways. Bulk removal of Ca 2+ following such signaling events is accomplished by members of the Ca 2+ :cation (CaCA) superfamily      . The CaCA superfamily includes the Na + /Ca 2+ (NCX) and Ca 2+ /H + (CAX) antiporters, and in mammals the NCX and related proteins constitute families SLC8 and SLC24, and aredoi:10.3410/f.718028166.793480004 fatcat:gby6udmlhbcqpgdxemj6lurflu