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Distribution of grey matter atrophy in Huntington's disease patients: A combined ROI-based and voxel-based morphometric study
2006
NeuroImage
The striatum, a subcortical structure, is the principal target of the neurodegenerative process in Huntington's disease (HD). The measurement of striatal atrophy using the bicaudate ratio on CT scanner images has therefore been used for years to assess disease progression, but this measure only takes into account unidimensional changes in the head of the caudate nucleus. Recently, voxel-based morphometry (VBM), which permits automated statistical comparisons of whole-brain MRI images, has been
doi:10.1016/j.neuroimage.2006.05.057
pmid:16875847
fatcat:unx3fgozgfgcdfeajan4ykmpra