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Production of Interferon-like Inhibitor Induced by Extract from Rous Sarcoma. I. Inhibition of Rous Sarcoma Virus Infection and Properties of the Inhibitor Produced
UNiMAm' Chick embryo cells treated \\'it11 RNA preparatioiT from Rous sarcoma tissues had reduced susceptibility to infectioiT by Rous sarcoma virus (RS\;), Bryan's ITiglT titer strain. 'I'he same RNA preparation induced chick embr o cells to produce an inhibitor of gro\^th of RS\I in the culture medium. This inducin substance \\, as resistant to ribonuclease (RNase) and deoxyribonuclcase (DI. :asc). The inhibitor produced \\, as shown to be ITon-dialyzable, and to be destroyed b trypsiiT ordoi:10.18910/82868 fatcat:ugyq6b3g55ew5gclp3mqr2rp5y