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Background. Chronic fatigue syndrome and fibromyalgia continue to be perplexing conditions of unknown validity. Aetiological and symptomatic heterogeneity is likely and the distinctiveness of these disorders remains unclear. Our aims were to investigate empirically symptomatic heterogeneity in chronic fatigue syndrome and fibromyalgia. Methods. Latent class analysis was applied to data from 646 patients who met accepted criteria for chronic fatigue syndrome and\or fibromyalgia who weredoi:10.1017/s0033291702005834 pmid:12171382 fatcat:f6q23vfdr5ghfdnbgmavsr4kse