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Colchicine causes prenatal cell toxicity and increases tetraploid risk
[post]
2019
unpublished
Colchicine is a clinical medicine used for relief from gout and familial Mediterranean fever. Because of its toxic effects, intravenous injection of colchicine has been banned, but it is still widely administered orally. We assayed the toxic effects of colchicine in cultured primary chorionic villus cells and amniotic fluid cells to interpret its influence on the placenta and foetus. Methods Bright field record and cell count kit 8 were used to value cell viability. Flow cytometer was used to
doi:10.21203/rs.2.13119/v3
fatcat:soa3q3byu5g7floec7la75h254