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Comparative toxicity of different cereals for gluten-intolerant individuals. Coeliac disease is caused by prolamines, the storage proteins of some cereals, located in the endosperm. Cereals do not all have the same toxicity. The four wheat prolamine groups (v., 3, y and M gliadins), visible in electrophoresis at acid pH, have been isolated and their toxicities compared by observing the. morphological changes in intestinal biopsies cultured in vitro when peptic-tryptic digests of the studieddoi:10.1051/rnd:19800728 fatcat:yevghpbq35gchfssxc4g4pt7nq