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Co-evolutionary Models for Reconstructing Ancestral Genomic Sequences: Computational Issues and Biological Examples
[chapter]
2009
Lecture Notes in Computer Science
The inference of ancestral genomes is a fundamental problem in molecular evolution. Due to the statistical nature of this problem, the most likely or the most parsimonious ancestral genomes usually include considerable error rates. In general, these errors cannot be abolished by utilizing more exhaustive computational approaches, by using longer genomic sequences, or by analyzing more taxa. In recent studies we showed that co-evolution is an important force that can be used for significantly
doi:10.1007/978-3-642-04744-2_14
fatcat:epeqwgirnngcxdgjnjdlhioyka