Quantitative genetics in the age of omics

Joost JB Keurentjes, Maarten Koornneef, Dick Vreugdenhil
2008 Current opinion in plant biology  
The use of natural variation in the genetic dissection of quantitative traits has a long-standing tradition. Recent advances in high-throughput technologies for the quantification of biological molecules have shifted the focus in quantitative genetics from single traits to comprehensive largescale analyses. So-called omic technologies now enable geneticists to take a look in the black box that translates genetic information into biological function. These processes include transcriptional and
more » ... ost) translational regulation as well as metabolic signaling pathways. The progress made in analytical and statistical techniques now allows the construction of regulatory networks that integrate the different levels of the biological information flow from gene-to-function.
doi:10.1016/j.pbi.2008.01.006 pmid:18325828 fatcat:hvmyriqb6bdbbhgh2doec3f25m