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2013): Role of mica repeat polymorphism in the manifestation of type 1 diabetes mellitus in Bengali Indian patients. Genetika, Vol 45, No. 2, 611-619. Background. The major histocompatibility complex class I chain-related gene A (MICA) (OMIM-600169) is a polymorphic gene in the HLA region expressed mainly by epithelial cells. The MICA protein encoded by the allele influences the activation of NK cells, which modify β-cells destruction and has been found to be involved in susceptibility of T1DM.doi:10.2298/gensr1302611r fatcat:kk2yq7mcrvdhfjxtxi3xw637tu