Efficient Synthesis of 5(4H)-Imidazolones and in vitro Antifungal Activity Studies Against Selected Phytopathogens

2014 Asian Journal of Chemistry  
A series of five new 1-(substituted phenyl)-2-phenyl-4-(substituted benzylidine)imidazole-5-one derivatives (or) 5(4H)-imidazolones have been synthesized adopting SiO2, Al2O3-90 and Y-faujasite (Y-H type) zeolite as catalysts. These compounds were assayed for their antifungal activity on three different selected phytopathogens which disparately affects the Jowar crop (Sorghum vulgare) of poaceae family. Among the screened target molecules, compound 18 exhibited potent inhibitory activity
more » ... d to the standard drug bavistine, which is worth for further investigation.
doi:10.14233/ajchem.2014.15893 fatcat:4kgl7ott6nes7eeyzo3hhphrgy