The covid-19 pandemic continues to be a global health problem. Daily reports provide more insight into your natural history. The objective of this study is to evaluate and analyze the dynamics of the clinical-epidemiological characteristics of patients with COVID-19, according to their vital status (alive or deceased). Materials and Methods : 98 patients were evaluated, divided into two groups: 81 alive and 17 deceased. It is an observational, analytical, case report type study from March 7 to

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... une 20, 2020. The variables were compared with the chi-square test, Yates or Fisher's exact test, as appropriate. The magnitude of risk was expressed in Odds Ratio. Signifi cance was established at p ≤ 0.05. Results: The most frequent age group was 30-59 years (51.8% vs. 17.6, p = 0.0100), as well as males (69.4% vs. 52.9%, p = 0.564). The symptomatic were the majority (67.9% vs. 88.2%, p=0.254). In the deceased group, general malaise (93,3%) was the main symptom. Risk factors were found less frequently in living than deceased patients (62.9% vs. 94.1%, p = 0.033). Most patients had accumulated 2 risk factors (52.9% vs. 58.8%, p = 0,142), with an Old Ratio of 1.481 (95% CI: 0.468-4.687). Conclusion: The COVID-19 pandemic is a disease with similar clinical and epidemiological characteristics in world populations, in most temporary scenarios. Current reports should provide information to re-evaluate interventions and modify them if they do not meet public health policy goals.