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Effects of Low-Dose Prednisolone on Hepatic and Peripheral Insulin Sensitivity, Insulin Secretion, and Abdominal Adiposity in Patients With Inflammatory Rheumatologic Disease

Carolyn J. Petersons, Brenda L. Mangelsdorf, Arthur B. Jenkins, Anne Poljak, Malcolm D. Smith, Jerry R. Greenfield, Campbell H. Thompson, Morton G. Burt
2013 Diabetes Care  
RESEARCH DESIGN AND METHODSdSubjects with inflammatory rheumatologic disease without diabetes mellitus were recruited.  ...  Basal endogenous glucose production (EGP) was estimated by 6,6-2 H 2 glucose infusion, insulin sensitivity was estimated by two-step hyperinsulinemic-euglycemic clamp, insulin secretion was estimated by  ...  They are prescribed longterm to ;0.75% of the general population, most frequently to patients with inflammatory rheumatologic disease (1) .  ... 
doi:10.2337/dc12-2617 pmid:23670996 pmcid:PMC3747874 fatcat:hmauvebkgrdtdo7paebajd6pji