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novoPathFinder: a webserver of designing novel-pathway with integrating GEM-model

Shaozhen Ding, Yu Tian, Pengli Cai, Dachuan Zhang, Xingxiang Cheng, Dandan Sun, Le Yuan, Junni Chen, Weizhong Tu, Dong-Qing Wei, Qian-Nan Hu
2020 Nucleic Acids Research  
Besides, more efficient pathways with novel reactions could also be retrieved for further experimental exploration. novoPathFinder is available at http://design.rxnfinder.org/novopathfinder/.  ...  However, with the large number of reactions that existed in the metabolic space and complicated metabolisms within hosts, identifying novel pathways linking two molecules or heterologous pathways when  ...  The integration of kinetic information with GEM-models would improve this phenomenon.  ... 
doi:10.1093/nar/gkaa230 pmid:32313937 fatcat:ll7zga3e7nfgreveblnu3cbpli