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mAPC-GibbsOS: an integrated approach for robust identification of gene regulatory networks

Xu Shi, Jinghua Gu, Xi Chen, Ayesha Shajahan, Leena Hilakivi-Clarke, Robert Clarke, Jianhua Xuan
2013 BMC Systems Biology  
Conclusions: We have developed a two-step approach for gene regulatory network identification, featuring an integrated method to identify modularized regulatory structures and refine their target genes  ...  Identification of cooperative gene regulatory network is an important topic for biological study especially in cancer research.  ...  Methods mAPC-GibbsOS is an integrative method that focuses on identifying modularized gene regulatory network.  ... 
doi:10.1186/1752-0509-7-s5-s4 pmid:24564939 pmcid:PMC4028818 fatcat:h3aa3ik5xnd3dbq5zghbeuhwby