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CLIN-RADIATION THERAPY

W.-S. Yoon, J.-T. Kim, Y.-M. Han, D.-S. Chung, Y.-S. Park, K. J. Lizarraga, M. Allen-Auerbach, A. A. De Salles, W. H. Yong, W. Chen, M. I. Ruge, P. Kickingereder (+232 others)
2012 Neuro-Oncology  
Glomus jugulare tumours (GJTs) are rare tumours that arise from the paraganglion chief cells of chemoreceptor bodies found in the adventia of the jugular vein. The incidence of GJTs is 1/30,000 in the healthy population and 1/1-1.3 million in the general population. Stereotactic radiotherapy (SRT) and stereotactic radiosurgery (SRS) have been used to treat GJTs with very promising results. Between 2003 and 2011, 10 patients (2 male, 8 female) were treated with SRT for GJTs at our tertiary care
more » ... our tertiary care centre. The mean age at the onset of treatment was 51.9 years (median 54.5, range 35-72.) Six of the ten patients (60%) presented with a previously untreated GJT. SRT was delivered using the BrainLab linear accelerator system with conformal 6-MV photon beams across 25 fractions over 5 weeks. Seven patients were treated with 5625 cGy (4500 cGy at the 80% isodose line). Three patients were treated with 6250 cGy (5000 cGy at the 80% isodose line). The mean follow-up time was 31.7 months (median 21 months; range 6-72 months). Tumour control was achieved in 100% of patients. None of the tumours grew or recurred during the follow-up period. Tumor volume decreased in all patients. The mean pre-SRT tumor volume was 9.93 + 3.2 cm 3 , and the mean post-SRT tumor volume was 4.41 + 3.
doi:10.1093/neuonc/nos238 fatcat:fixfroykindbbcjlrvha2mjoh4