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We combined clinical, cytokine, genomic, methylation and dietary data from 43 young adult monozygotic twin pairs (aged 22 – 36, 53% female), where 25 of the twin pairs were substantially weight discordant (delta BMI > 3kg/ m2). These measurements were originally taken as part of the TwinFat study, a substudy of The Finnish Twin Cohort study. These five large multivariate data sets (comprising 42, 71, 1587, 1605 and 63 variables, respectively) were jointly analysed using an integrative machinedoi:10.1101/2019.12.19.19015347 fatcat:op4f2dbwsfcllcm4z5y57pflbe