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Stochastic Global Model for the Prediction of the Asymptotic CSDs Using Antisolvent Crystallization Processes

G. Cogoni, S. Tronci, G. Mistretta, R. Baratti, J. Romagnoli
2013 Chemical Engineering Transactions  
A stochastic global formulation for the description of antisolvent mediated crystal growth processes is discussed based on the Fokker-Planck equation (FPE). The obtained global model is used to define an operating map of the crystallization process, where asymptotic iso-mean and iso-variance curves are reported in an antisolvent flowrate – temperature plane. Using the obtained asymptotic operational map, three different CSDs have been predicted and compared, both in asymptotic and then dynamic
more » ... c and then dynamic conditions, using experimental results.
doi:10.3303/CET1332352 doaj:3de1fab2f7ff4af2b2e9c82cc20d10ee fatcat:mvr2vrytine6nhjgxgatxwl3cu