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Indian Journal of Chemical Technology
Ibuprofen chitosan (CS) /montmorillonite (MMT) microspheres have been produced by an ion cross-linking technique under microwave irradiation. The morphology and mechanical strength of the microspheres are significantly improved due to the use of chitosan as a drug carrier. Also, in comparison with other cross linker reagents, the effect of adsorption can be increased by the use of a small amount of sodium pyrophosphate. Furthermore, an orthogonal design method has been applied in order tofatcat:zjpvy7n3bna77lp2mcfreafumi