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Invasive Amebiasis as an Emerging Parasitic Disease in Patients With Human Immunodeficiency Virus Type 1 Infection in Taiwan

Chien-Ching Hung, Hung-Yin Deng, Wei-Hung Hsiao, Szu-Min Hsieh, Chin-Fu Hsiao, Mao-Yuan Chen, Shan-Chwen Chang, Kua-Eyre Su
2005 Archives of Internal Medicine  
Whether risk of invasive amebiasis due to Entamoeba histolytica is higher among human immunodeficiency virus (HIV)-infected persons than uninfected persons remains unclear, although intestinal colonization by Entamoeba dispar is common among men who have sex with men. Our objective was to determine the prevalence of invasive amebiasis and intestinal colonization by E histolytica and E dispar in HIV-infected persons and uninfected controls. Methods: We assessed the prevalence of invasive
more » ... of invasive amebiasis by case review of 951 HIV-infected persons and by serologic studies of 634 of the 951 HIV-infected persons, 429 uninfected controls with gastrointestinal symptoms, and 178 uninfected healthy controls using indirect hemagglutination antibody assay. We assessed the rate of intestinal colonization by E histolytica and E dispar by fecal antigen and polymerase chain reaction tests in 332 asymptomatic HIV-infected persons and 144 of the 178 uninfected healthy controls.
doi:10.1001/archinte.165.4.409 pmid:15738369 fatcat:ftdwznmoyrblth5tit5b3h3t6u