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Towards ultrasound travel time tomography for quantifying human limb geometry and material properties

Jonathan R. Fincke, Micha Feigin, Germán A. Prieto, Xiang Zhang, Brian Anthony, Neb Duric, Brecht Heyde
2016 Medical Imaging 2016: Ultrasonic Imaging and Tomography  
Towards ultrasound travel time tomography for quantifying human limb geometry and material properties," Proc. SPIE 9790, Medical Imaging ABSTRACT Sound speed inversions made using simulated time of flight data from a numerical limb-mimicking phantom comprised of soft tissue and a bone inclusion demonstrate that wave front tracking forward modeling combined with 1 regularization could lead to accurate estimates of bone sound-speed. Ultrasonic tomographic imaging of limbs has the potential to
more » ... he potential to impact prosthetic socket fitting, as well as detect and track muscular dystrophy diseases, osteoporosis and bone fractures at low cost and without radiation exposure. Research in ultrasound tomography of bones has increased in the last 10 years, however, methods delivering clinically useful sound-speed inversions are lacking. Inversions for the sound-speed of the numerical phantoms using 1 and 2 regularizations are compared using wave front forward models. The simulations are based on a custom-made cylindrically-scanning tomographic medical ultrasound system (0.5 -5 MHz) consisting of two acoustic transducers capable of collecting pulse echo and travel time measurements over the entire 360° aperture. Generating clinically useful pulse-echo and sound-speed inversion images of regions of the body where bones are present leads to significant algorithmic and measurement challenges. These challenges are primarily exist because
doi:10.1117/12.2218387 fatcat:uygdh7wh4ffofbxxo6rikdv6ge