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Gastric Emptying of a Solid Meal Starts during Meal Ingestion: Combined Study Using 13C-Octanoic Acid Breath Test and Doppler Ultrasonography

Itta M. Minderhoud, Marco W. Mundt, Jan M.M. Roelofs, Melvin Samsom
2004 Digestion  
Scintigraphy and the 13 C-octanoic acid breath test are both applied to assess gastric emptying. Using the 13 C-octanoic acid breath test, excretion curves show 13 C excretion immediately after ingestion of a solid egg meal, in contrast with scintigraphy where gastric emptying is observed after a lag phase. The aim of our study was to investigate whether transpyloric flow occurs during and directly after meal ingestion. Therefore, transpyloric flow was measured during and after ingestion of an
more » ... er ingestion of an egg meal labeled with 13 Coctanoic acid, using Doppler ultrasonography. The breath test was performed simultaneously, with samples taken at regular intervals. The first emptying episode was observed 6.9 (3.9-16.2) min after start of meal ingestion. A significant relation between recovery of 13 C and total duration of gastric emptying during the first 20 min was observed (partial correlation coefficient r = 0.80, p <0.001). In conclusion, transpyloric flow starts during ingestion of a solid egg meal and results in detectable excretion of 13 C.
doi:10.1159/000080088 pmid:15297778 fatcat:hf5ceirmbvd37kccn2jh5abgga