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Impact of an Exercise Program on Arterial Stiffness and Insulin Resistance in Hemodialysis Patients

S. Mustata
2004 Journal of the American Society of Nephrology  
Cardiovascular disease remains the primary cause of mortality in patients who are maintained on hemodialysis. Arterial stiffness and insulin resistance are independent risk factors for cardiovascular mortality in this population. In healthy individuals, higher physical conditioning is associated with reduced arterial stiffness. Exercise reduces insulin resistance and glucose intolerance in sedentary, overweight individuals and diabetic patients. The purpose of this study was to determine the
more » ... to determine the impact of an exercise program on arterial stiffness and insulin resistance in a group of patients on hemodialysis. The effect of exercise training on arterial stiffness and insulin resistance in 11 patients who were on chronic hemodialysis was evaluated. Exercise classes of 1-h duration were conducted twice weekly for 3 mo. Arterial stiffness was assessed using the radial artery pressure waveform analysis. Aerobic exercise improved arterial stiffness from 17 Ϯ 3 u at
doi:10.1097/01.asn.0000140256.21892.89 pmid:15466276 fatcat:2xruvjvuxfcynm4wkfzc253wue