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A validated UV spectrophotometric determination of an antiviral drug zanamvir from tablet formulations

Bhaskar Reddy, G Subbareddy
Journal of Chemical and Pharmaceutical Research   unpublished
Simple, sensitive and specific spectrophotometric method was developed and validated for quantification of zanamvir in tablet dosage form. Drug showed the absorption maxima in water at 260nm and was linear for a range of 2-10,g/ml with a correlation coefficient of 0.9999. The validation of the above method was done by carrying out precision and accuracy studies. The Limit of detection and Limit of Quantification for zanamvir was found to be 0.82mcg/ml and 2.76mcg/ml. The percentage recovery was
more » ... entage recovery was found to be 99.3% and showed good repeatability with relative standard deviation less than 2. So, the proposed method can be applied for the routine analysis of zanamvir from formulations