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Effects of Variable Frequencies of Combined Proprioceptive and Kinesthesia, Balance and Agility Exercise Program in Adults With Knee Osteoarthritis: a Study Protocol for Randomized Controlled Trial [post]

Aysha I. Adhama, Mukadas O. Akindele, Aminu A. Ibrahim
2020 unpublished
Background:Knee osteoarthritis (OA) is a common painful and disabling condition that affects older individuals. Proprioceptive (PR) and kinesthesia, balance and agility (KBA) exercises are two neuromuscular training reported to be beneficial for individuals with knee OA. However, their combined effects have not been systematically evaluated. Moreover, the most optimal dosage of knee OA exercise-based programremains unclear. The aim of this study is to determine the combined effects of PR and
more » ... ffects of PR and KBA exercise program with different frequency of treatment sessions(i.e. twice weekly or thrice weekly) in adults with knee OA.Methods:A single (assessor) blind, three-arm parallel, multi-centerrandomized controlled trial will be conducted. Eighty-four adults with knee OA will be recruited from four tertiary hospitals in Northwestern Nigeria and randomly assigned into one of three intervention groups; group 1 (control or conventional physiotherapy; n = 28), group 2 (two sessions per week of combined PR and KBA exercise; n = 28), and group 3 (three sessions per week of combined PR and KBA exercise, n = 28). Participants in the conventional therapy group will receive two sessions of brief patient education, and 16 sessions of ultrasound therapy, and stretching, strengthening and aerobic exercise for 8 weeks. Participants in the two experimental groups will be treated for 8 weeks and will also receive the same conventional therapy. All groups will be assessed pre-intervention, immediately post-intervention and at 3-month, 4-month and 6-month post-randomization. The primary outcomes will be physical function and quality of life while the secondary outcomes will be pain intensity, knee stability and proprioception.Discussion:Findings of this study may provide evidence of effectiveness of combined PR and KBA exercise program for knee OA, which may serve as a basis for recommending the use of such multimodal exercise approachfor individuals with knee OA. The study may also provide evidence for the ideal number of sessions of knee OA exercise-based programsto achieve the highest effectiveness.Trial registration:Pan African Clinical Trials Registry, (PACTR201810713260138), Registered on 28 November 2017.
doi:10.21203/ fatcat:suk55hjga5dfzfbsdf6siyjtbm