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1825 The Lancet  
470 heated in a drachm or two of water, to produce, in the watery solution of the sulphate of quina, a copious preeipitate of a cinnamon brown colour. This precipitate dissolves on heating the liquor; it is also soluble in rectified spirit, and is again thrown down by water. The tincture of iodine may be also applied as a test of the sulphate of quina; this tincture is partly decomposed by water, but the colour of the precipitate is quite different from that produced by the sulphate of quina,
more » ... ulphate of quina, which in colour very much resembles the Peruvian bark. By the preceding characters, namely, its fusion by heat, little solubility in water; greater solubility in alcohol, and the brown coloured precipitate it affords with iodine, it may be distinguished from other substances. To these characters may be added, its sensible qualities, particularly its strong bitter taste, which, if found to co-exist with the above-mentioned chemical properties, will prove the substance to be genuine.
doi:10.1016/s0140-6736(02)83481-x fatcat:a7yz7tkdhrdx3nnyncqmymapae