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In this study, the biological activity and chemical composition of Bingöl propolis were investigated. The isolates, including ethanol isolate (EI), hexane isolate (HI), and essential oil isolate (EOI), were prepared from raw propolis. The lipophilic and volatile organic compounds in isolates were analyzed by Gas Chromatography-Mass Spectrometry (GS-MS) measurements. Bingöl propolis isolates showed antimicrobial activity against reference pathogen bacterial strains, including Staphylococcusdoi:10.46810/tdfd.776424 fatcat:hfwhertwpvhr5j3alihv566rxq