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Role of glutathione and other antioxidants in the inhibition of apoptosis and mesenchymal transition in rabbit lens epithelial cells

H.J. Wang, J. Zhu, G.Y. Zheng
2014 Genetics and Molecular Research  
This study aimed to discuss the effect and mechanism of glutathione (GSH) and catalase (CAT) on transforming growth factor beta (TGF-β)-induced lens epithelial cell (LEC) apoptosis and epithelial mesenchymal transition (EMT) to prevent and control cataracts. Healthy rabbits (4 weeks old) were randomly selected, and LECs from their lenses were cultured in vitro. The 2nd-and 3rdgeneration cells were divided into 6 groups (group A: 75 pg/mL TGF-β 2
doi:10.4238/2014.september.1.1 pmid:25222220 fatcat:kq3ttiee3fd3hcwh76pa6c5maa