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Evaluation of anti-inflammatory activity of selected legumes from Pakistan: in vitro inhibition of cyclooxygenase-2

Muhammad Zia-Ul-Haq, Premysl Landa, Zsófia Kutil, Mughal Qayum, Shakeel Ahmad
2013 Pakistan Journal of Pharmaceutical Sciences  
Crude methanolic extracts of selected legumes namely, black gram (Vigna mungo L.), green gram (Vigna radiata (L.) R. Wilczek ), soybean (Glycine max (L.) Merr.) and lentil (Lens culinaris Medik.) were investigated for anti-inflammatory effects, using COX-2 producing PGE(2) inhibitory assay. Percentage inhibition observed was 73.93, 79.84, 92.17 and 74.47 for black gram, green gram, soybean and lentil respectively at 20μg/ml extract concentration. The 100μg/ml concentration showed increase in
more » ... owed increase in the percent inhibition except for soybean. This is the first report on COX-2 inhibitory potential of food legumes.
pmid:23261746 fatcat:okig5st6dfberjeo3xjgradoam