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Synthesis of new dihydrospiro[quinoline-2,4'-piperidines] by a two-step synthetic route based on 4-piperidone imine reactivity is reported. An acetyl migration in 1-acetyl-1'-benzyl-4-methyl-3,4dihydrospiro[quinoline-2,4'-piperidines] under debenzylation conditions (HCOONH 4 /Pd/C/MeOH) is found.doi:10.2174/1570178053400234 fatcat:p555lgapqba77biastbtd2c7ri