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1885 BMJ (Clinical Research Edition)  
THB BBITISH MBDICUL tTOUBNAL.~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ elbows were in the same condition, except that the nodules were all smaller, and that the one on the left external condyle had disappeared. The right knee presented one over the internal condyle, and two over the external condyle ; while oni the left knee, there was one above the patella, two over the external, and one over the internal, condyle. On April 18th, the large nodule over the right external condyle was reduced to the
more » ... s reduced to the size of a pea, and there was still a nodule over the left internal condyle. The only other remaining nodule was very small, and was situated over the left olecranon. On May 9th, there was no change, except that the last-mentioned nodule had disappeared. There is little to be said about the temperature in this case ; there was slight pyrexia, and the temperature was usually observedl to be rather higher than usual before a fresh crop of nodules made its appearance. REMARKS BY DR. EDGE.-This case seems worthy of being placed oni record, as it is a typical examiple of the affection to which Drs. Barlow and Warner called attention in 1881. The symmetry of the nodules was very marked in this case, but this has not always been noticed. The case illustrates how much the nodules vary as regards duration, some lasting a few hours only, while others persist for several months. They are usually found in young subjects, from four to eighteen years old, and are then lnearly always associated with rheumatism arn(d heart-disease, the latter being frequently of a progressive character. They vary in number from one to fifty, about forty-four havinig been nloticed in this patient. These nodules often appear in successive crops, aind, as illustrated in the case in point, sometimes return after a temiporary disappearance. They are always more or less
doi:10.1136/bmj.1.1267.738 fatcat:b2vrmr3uofazfbc5tcoiqlrwgy