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The symbiotic fungus Leucoagaricus gongylophorus (Möller) Singer (syn. Rozites gongylophora Möller) cultivated by the leaf-cutting ant Atta sexdens L. had its development strongly inhibited by crude extracts obtained from leaves of sesame, Sesamum indicum L. (Pedaliaceae). With most of the fractions from these extracts total inhibition was observed at 2.5 mg/ml, whereas inhibition of 50% was observed with some fractions at 1.25 mg/ml. Chromatographic analysis of the hexane extract showed thatdoi:10.1590/s0301-80591998000300010 fatcat:bjbbjprl2fbuhlx3av5xv3mcnu