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Leprosy is a still a serious human health problema in developed countries. Environmental and genetic factors are playing a key role in the chronic course of the disease, resistance versus susceptibility. The multidrug treatment is not effective for all infected individuals; "cured" individuals mostly show relapses of neurological disordes and potential as the same as not cured can present physical and deformed constrainst. The unsolved puzzle in leprosy is that clinic spectrum depends of thedoi:10.24294/ti.v3.i1.1122 fatcat:cajyevdi2ncblmkjuaekmybmhm