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CORRELATION OF WEIGHT LOSS WITH INFERTILITY FOLLOWING SLEEP DEPRIVATION IN ALBINO RATS

Ugwuene Fo, Alumana Eo, Joshua Pe
2016 unpublished
Body weight is the total mass or weight of a person or animal obtained without any external factor than the component of the body. Overweight or underweight may influence the fertility status of either animal or human as the case may be. The aim of this study is to determine whether weight loss has any correlation with male or female infertility. Twenty four Wister albino rats were sleep deprived and used in this study. The albino rats were certified healthy before sleep deprivation. Body
more » ... ivation. Body weight of the rats were measured before and after sleep deprivation. The pre sleep deprivation body weight values of the albino rats served as control for weight loss. Serum specimen was also collected from the rats before and after sleep deprivation for the assay of some fertility hormones. The pre sleep deprivation assay results of the fertility hormones equally served as control for post sleep deprivation status of the fertility hormones. The fertility hormones assayed include follicle stimulation hormone (FSH), luteinizing hormone (LH), Prolactin, thyroid stimulating hormone (TSH), Testosterone and estradiol. The results showed a significant decrease (P<0.05) in body weight of albino rats after sleep deprivation when compared with the control. There were significant decreases (P<0.05) in testosterone, estradiol, prolactin and TSH serum levels after sleep deprivation when compared with their controls respectively, while there were no significant changes (P>0.05) in the serum level of FSH and LH. These results indicate that all other relevant factors being equal, body weight loss has negative effect on male and female fertility, using body weight and fertility hormone as indices.
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